Paracetamol heckel plot

15 Jan 2013 The Heckel equation4 is widely used for relating the relative density, D . The Heckel plots for paracetamol tablets containing. 10(wv) binder common analgesic drugs ibuprofen and acetaminophen were prepared. Preformulation studies Crystal habit Heckel-plot Ibuprofen Acetaminophen

2.400. 2.800. 3.200. 3.600. 4.000. Tablet thickness (mm). Heckel plot for Avicel PH-101 and paracetamol obtained on the GTP-1. Paracetamol. Avicel PH101. 4

obtained from Cissus populnea (Vitaceae), in paracetamol tablet formulations in comparison with . Figure 1 shows representative Heckel plots for paracetamol on a paracetamol tablet formulation39s compressional character- istics and Figure 1: Heckel plots for paracetamol tablet formulations containing 5.0 ww of Low correlation coefficients of the initial parts of the Heckel plots, a low strain rate main mechanism during the compaction of paracetamol was fragmentation


8 Aug 2014 Keywords: Goat fat, magnesium stearate, Heckel plot, Kawakita plot, tensile paracetamol tablets has shown that goat fat enhances the the initial parts of the Heckel plots, a low strain rate sensitivity, and an increase in mean yield . Typical Heckel plot for paracetamol (105. 210-m sample) at a

29 Mar 2007 However, Odeku and Itiola (31) while working on the compressional properties of paracetamol tablet formulations found that the Heckel plots Key words: Grewia gum, PVP, paracetamol, Heckel equation, Kawakita equation, compaction friability. The Heckel plot is the method most frequently used to