Tetracycline drug resistance

Three different specific mechanisms of tetracycline resistance have been identified so far: tetracycline efflux, ribosome protection and tetracycline modification Feb 12, 2013 Tetracycline resistance protein Tet(O), which protects the bacterial ribosome from binding the antibiotic tetracycline, is a translational GTPase

Cells become resistant to tetracycline by at least three is added to the molecule , causing inactivation of the drug

Tetracycline has been a widely used antibiotic because of its low toxicity and broad spectrum of activity. However, its clinical usefulness has been declining Tetracycline binding is reversible, therefore diluting out the antibiotic can reverse its effects. Tetracycline resistance genes are often located on mobile elements, Antimicrobial Drug Resistance Tetracycline resistance (Tcr) is most often due to the acquisition of new genes, which code for energy-dependent effl ux of

Tetracycline resistance - Antibiotic resistance - Main Page

the antibiotic, and 2 protection of ribosomes. Further mechanisms of tetracycline resistance include enzymatic inactivation of antibiotic, permeability barriers, Tetracycline resistance now occurs in an increasing number of pathogenic, .. Export of tetracycline reduces the intracellular drug concentration and thus

Escherichia coli and Antibiotic Resistance to Tetracycline Antibiotics. Bacterial antibiotic resistance. The phenomenon of bacterial drug resistance was first To reduce the development of drug-resistant bacteria and maintain the effectiveness of Tetracycline hydrochloride and other antibacterial drugs, Tetracycline